Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine → 2-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-1,2,3,4-tetrahydroisoquinoline-7-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine | HCID 1484519 | — |
| 반응물 | 7-Cyano-1,2,3,4-tetrahydroisoquinoline | HCID 10176243 | — |
| 생성물 | 2-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-1,2,3,4-tetrahydroisoquinoline-7-carbonitrile | HCID 59402280 | — |
반응 단계
This compound was prepared by using procedures analogous to those described for the synthesis of Example 1 starting from 4-chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine and 1,2,3,4-tetrahydroisoquinoline-7-carbonitrile (Asta Tech, Cat. No. 48330). LCMS (M+H)+: m/z=350.2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08436008B2 |
| 출처 데이터셋 | uspto-grants-2013_05 |
| ORD ID | ord-78604d54908c4b7296443f09674ebd41 |
| 출처 메모 | uspto-grants-2013_05 |