참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Oxirane, 2-((tetradecyloxy)methyl)- | HCID 38190 | — |
| 반응물 | Sodium ethoxide | HCID 2723922 | — |
| 생성물 | 1-Tetradecyl-3-ethylglycerol | HCID 86652916 | 319.6% |
반응 단계
Under nitrogen stream, 30 g of sodium ethoxide was added to 851.8 g (18.5 mol) of ethanol, and the mixture was heated to 80° C. Then, 500 g (1.85 mol) of tetradecyl glycidyl ether were added dropwise thereto. The mixture was stirred for 18 hours at the same temperature. Thereafter, ethanol was distilled off, and 10.8 g of 85% phosphoric acid was added thereto, followed by washing the resultant mixture with water three times. After water washing, distillation was performed under reduced pressure, to thereby obtain 446 g of 1-tetradecyl-3-ethylglycerol (yield 76.2%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08440645B2 |
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| 출처 데이터셋 | uspto-grants-2013_05 |
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| ORD ID | ord-7de36ed9740c418595431acf70cab376 |
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| 출처 메모 | uspto-grants-2013_05 |
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