1-(3,5-Dibromophenyl)ethanone → (r)-1-(3,5-Dibromo-phenyl)-ethanol

HRID 2092490

반응식

HRID 2092490 반응식
[Br:1][C:2]1[CH:3]=[C:4]([C:9](=[O:11])[CH3:10])[CH:5]=[C:6]([Br:8])[CH:7]=1.B1(C)OC(C2C=CC=CC=2)(C2C=CC=CC=2)[C@H]2N1CCC2>>[Br:1][C:2]1[CH:3]=[C:4]([C@H:9]([OH:11])[CH3:10])[CH:5]=[C:6]([Br:8])[CH:7]=1

참가 물질

3

반응물 2

HCID 6218251-(3,5-Dibromophenyl)ethanoneHCID 2734713(3aS)-1-methyl-3,3-diphenyl-hexahydropyrrolo(1,2-c)(1,3,2)oxazaborole

생성물 1

HCID 58539463(r)-1-(3,5-Dibromo-phenyl)-ethanol

실험 절차

1-(3,5-dibromo-phenyl)-ethanone and (S)-(−)-2-methyl-CBS-oxazaborolidine were reacted as described in Example 35, Step 1 to provide (R)-1-(3,5-dibromo-phenyl)-ethanol.

출처 및 근거

ORD 기록
ord-a3746b822b54429db57ae5da9339f211
출처 데이터셋
uspto-grants-2013_05
특허 번호
US08440707B2

연결된 노트

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