Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nitro-4-(2,2,2-trifluoro-1-methyl-ethoxy)-benzene → 4-(2,2,2-Trifluoro-1-methyl-ethoxy)-aniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nitro-4-(2,2,2-trifluoro-1-methyl-ethoxy)-benzene | HCID 66577895 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-(2,2,2-Trifluoro-1-methyl-ethoxy)-aniline | HCID 66277568 | 98.6% |
반응 단계
Nitro-4-(2,2,2-trifluoro-1-methyl-ethoxy)-benzene (6.74 g) was dissolved in MeOH (70 mL). Pd on carbon (10% Pd, 500 mg) was added and the mixture was hydrogenated at RT for 12 hours. The suspension was filtered and the filtrate was concentrated in vacuo to provide the title compound as a brown liquid (5.8 g). Rf: 0.38 (silica gel, ether/heptane 1:1). MS (m/e): 206.1 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08440710B2 |
| 출처 데이터셋 | uspto-grants-2013_05 |
| ORD ID | ord-2d8ee7dcd7514d0fa0a82721d3c39024 |
| 출처 메모 | uspto-grants-2013_05 |