Ethyl 4-chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate → 4-[4-Methoxy-2-(2-methoxy-ethoxy)-phenyl]-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid ethyl ester
반응식
[CH2:1]([O:3][C:4]([C:6]1[C:10]2[N:11]=[CH:12][N:13]=[C:14](Cl)[C:9]=2[NH:8][CH:7]=1)=[O:5])[CH3:2].[CH3:16][O:17][C:18]1[CH:23]=[CH:22][C:21](B2OC(C)(C)C(C)(C)O2)=[C:20]([O:33][CH2:34][CH2:35][O:36][CH3:37])[CH:19]=1>>[CH2:1]([O:3][C:4]([C:6]1[C:10]2[N:11]=[CH:12][N:13]=[C:14]([C:21]3[CH:22]=[CH:23][C:18]([O:17][CH3:16])=[CH:19][C:20]=3[O:33][CH2:34][CH2:35][O:36][CH3:37])[C:9]=2[NH:8][CH:7]=1)=[O:5])[CH3:2]참가 물질
3
실험 절차
Starting from 4-chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid ethyl ester and 2-[4-methoxy-2-(2-methoxy-ethoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (example A43) the title compound is obtained as colorless solid.
출처 및 근거
- ORD 기록
- ord-00544cba39614b23bf65f0313032d56c
- 출처 데이터셋