1-(4-Aminopiperidin-1-yl)-2-methoxyethan-1-one → HCID 66866482, 화합물

반응식

[C:1]([C:4]1[CH:5]=[CH:6][C:7]([O:22][CH2:23][CH:24]2[CH2:26][CH2:25]2)=[C:8]([C:10]2[C:11]3[NH:18][CH:17]=[C:16]([C:19]([OH:21])=O)[C:12]=3[N:13]=[CH:14][N:15]=2)[CH:9]=1)(=[O:3])[CH3:2].[NH2:27][CH:28]1[CH2:33][CH2:32][N:31]([C:34](=[O:38])[CH2:35][O:36][CH3:37])[CH2:30][CH2:29]1>>[CH3:37][O:36][CH2:35][C:34]([N:31]1[CH2:30][CH2:29][CH:28]([NH:27][C:19]([C:16]2[C:12]3[N:13]=[CH:14][N:15]=[C:10]([C:8]4[CH:9]=[C:4]([C:1](=[O:3])[CH3:2])[CH:5]=[CH:6][C:7]=4[O:22][CH2:23][CH:24]4[CH2:26][CH2:25]4)[C:11]=3[NH:18][CH:17]=2)=[O:21])[CH2:33][CH2:32]1)=[O:38]

참가 물질

반응물 2

HCID 167779121-(4-Aminopiperidin-1-yl)-2-methoxyethan-1-one

HCID 66866059HCID 66866059, 화합물

생성물 1

HCID 66866482HCID 66866482, 화합물

실험 절차

Starting from 4-(5-acetyl-2-cyclopropylmethoxy-phenyl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (example A81) and 1-(4-amino-piperidin-1-yl)-2-methoxy-ethanone (A192) the title compound is obtained as colorless solid.

출처 및 근거

ORD 기록: ord-39f310badd4546fe8627c0113cb4aec0
출처 데이터셋: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08445501B2

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