Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(R)-2-(3,4-Dichloro-phenylamino)-propionic acid → 3-(3-Chloro-4-trifluoromethyl-phenylamino)-propionic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (R)-2-(3,4-Dichloro-phenylamino)-propionic acid | HCID 182146 | — |
| 반응물 | tert-Butyl 3-bromopropionate | HCID 256128 | — |
| 반응물 | 4-Bromo-2-chlorobenzotrifluoride | HCID 20269848 | — |
| 생성물 | 3-(3-Chloro-4-trifluoromethyl-phenylamino)-propionic acid tert-butyl ester | HCID 67074412 | 53% |
반응 단계
In analogy to the procedure described for intermediate 31, 4-bromo-2-chloro-1-trifluoromethyl-benzene and tert-butyl 3-bromopropionate gave the title compound in 53% yield as yellow oil. MS: 323 (M+, Cl).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08445674B2 |
| 출처 데이터셋 | uspto-grants-2013_05 |
| ORD ID | ord-03b14744d21f4c648d78db792fac9c37 |
| 출처 메모 | uspto-grants-2013_05 |