1-Isocyanato-3-(trifluoromethoxy)benzene → (4S)-6-Azaspiro[2.5]octan-4-ol hydrochloride
반응식
N(C1C=CC=C(OC(F)(F)F)C=1)=C=O.[Cl:15][C:16]1[CH:17]=[C:18]([N:26]2[CH2:31][CH2:30][N:29]([C@H:32]([CH2:38][O:39][CH3:40])[CH2:33][CH2:34][C:35](O)=[O:36])[C:28](=[O:41])[C@@H:27]2[CH3:42])[CH:19]=[CH:20][C:21]=1[C:22]([F:25])([F:24])[F:23].[CH2:43]1[C:45]2([CH2:50][CH2:49][NH:48][CH2:47][C@H:46]2[OH:51])[CH2:44]1>CCCCCCC.C(O)(C)C>[ClH:15].[CH2:21]1[C:20]2([CH2:19][CH2:18][NH:26][CH2:27][C@H:28]2[OH:41])[CH2:22]1.[Cl:15][C:16]1[CH:17]=[C:18]([N:26]2[CH2:31][CH2:30][N:29]([C@H:32]([CH2:38][O:39][CH3:40])[CH2:33][CH2:34][C:35]([N:48]3[CH2:49][CH2:50][C:45]4([CH2:43][CH2:44]4)[C@H:46]([OH:51])[CH2:47]3)=[O:36])[C:28](=[O:41])[C@@H:27]2[CH3:42])[CH:19]=[CH:20][C:21]=1[C:22]([F:24])([F:25])[F:23]
