Dichloromethane → N-(3-(4-(1H-indazol-5-ylamino)quinazolin-2-yl)phenyl)morpholine-4-carboxamide

반응식

[Cl:43][CH2:44][Cl:45].[O:1]1[CH2:2][CH2:3][N:4]([C:7](=[O:8])[NH:9][c:10]2[cH:11][c:12](-[c:16]3[n:17][c:18]4[cH:19][cH:20][cH:21][cH:22][c:23]4[c:24]([NH:26][c:27]4[cH:28][c:29]5[cH:30][n:31][n:32]([C:36]([O:37][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:42])[c:33]5[cH:34][cH:35]4)[n:25]3)[cH:13][cH:14][cH:15]2)[CH2:5][CH2:6]1>>[O:1]1[CH2:2][CH2:3][N:4]([C:7](=[O:8])[NH:9][c:10]2[cH:11][c:12](-[c:16]3[n:17][c:18]4[cH:19][cH:20][cH:21][cH:22][c:23]4[c:24]([NH:26][c:27]4[cH:28][c:29]5[cH:30][n:31][nH:32][c:33]5[cH:34][cH:35]4)[n:25]3)[cH:13][cH:14][cH:15]2)[CH2:5][CH2:6]1

참가 물질

반응물 2

HCID 6344Dichloromethane

HCID 59361923tert-butyl 5-(2-(3-(morpholine-4-carboxamido)phenyl)quinazolin-4-ylamino)-1H-indazole-1-carboxylate

생성물 1

HCID 59361906N-(3-(4-(1H-indazol-5-ylamino)quinazolin-2-yl)phenyl)morpholine-4-carboxamide

출처 및 근거

ORD 기록: ord-8f63d9a0c28a4dc38fda4aef00fc5d9c
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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