Isopropyl iodide → 4-Bromo-2-isopropoxy-1-methoxybenzene

반응식

[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:9][CH3:10])=[C:6]([OH:8])[CH:7]=1.[CH:11](I)([CH3:13])[CH3:12]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:9][CH3:10])=[C:6]([O:8][CH:11]([CH3:13])[CH3:12])[CH:7]=1

참가 물질

반응물 2

HCID 6362Isopropyl iodide

HCID 1422285-Bromo-2-methoxyphenol

생성물 1

HCID 467389524-Bromo-2-isopropoxy-1-methoxybenzene수율 86%

실험 절차

Reaction and post treatment were carried out in the same manner as in Reference Example 7-(a) except for using 10.1 g (49.8 mmol) of 5-bromo-2-methoxyphenol, and using 15 ml of isopropyl iodide in place of 1-bromo-2-chloroethane, whereby 10.4 g of the title compound was obtained as a pale yellowish solid. (Yield: 86%)

후처리

customReaction and post treatment

출처 및 근거

ORD 기록: ord-a32da5b587a54276a8e4474713d739eb
출처 데이터셋: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08450319B2

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