2-(Isoquinolin-5-YL)acetic acid → HCID 52944909, 화합물

반응식

[NH2:1][C:2]1[S:6][CH:5]=[N:4][C:3]=1[C:7]([O:9][CH3:10])=[O:8].[CH:11]1[C:20]2[C:15](=[C:16]([CH2:21][C:22](O)=[O:23])[CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][N:12]=1>>[CH:11]1[C:20]2[C:15](=[C:16]([CH2:21][C:22]([NH:1][C:2]3[S:6][CH:5]=[N:4][C:3]=3[C:7]([O:9][CH3:10])=[O:8])=[O:23])[CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][N:12]=1

참가 물질

반응물 2

HCID 120187082-(Isoquinolin-5-YL)acetic acid

HCID 53408092Methyl 5-amino-1,3-thiazole-4-carboxylate

생성물 1

HCID 52944909HCID 52944909, 화합물

실험 절차

Methyl 5-(2-(isoquinolin-5-yl)acetamido)thiazole-4-carboxylate was prepared from methyl 5-aminothiazole-4-carboxylate (0.132 g, 0.834 mmol) and 2-(isoquinolin-5-yl)acetic acid (0.163 g, 0.834 mmol) according to protocol A. Retention time (min)=2.400, method [3], MS (ESI) 328.0 (M+H).

출처 및 근거

ORD 기록: ord-2f9d5ad69ae84205a3d854e3b3908216
출처 데이터셋: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08450363B2

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