Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2-Cyclopropylcarbamoyl-2-hydroxy-1,1-dimethylethyl)-carbamic acid tert-butyl ester → 3-amino-N-cyclopropyl-2-hydroxy-3-methylbutanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2-Cyclopropylcarbamoyl-2-hydroxy-1,1-dimethylethyl)-carbamic acid tert-butyl ester | HCID 67385732 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Trifluoroacetic acid | HCID 6422 | — |
| 생성물 | 3-amino-N-cyclopropyl-2-hydroxy-3-methylbutanamide | HCID 57562093 | — |
반응 단계
A solution of (2-cyclopropylcarbamoyl-2-hydroxy-1,1-dimethylethyl)-carbamic acid tert-butyl ester in CH2Cl2 (10 mL) and TFA (5 mL) was stirred at room temperature for 4 h. The reaction mixture was then concentrated and chased with toluene to yield 3-amino-N-cyclopropyl-2-hydroxy-3-methylbutyramide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08450373B2 |
| 출처 데이터셋 | uspto-grants-2013_05 |
| ORD ID | ord-7a267b3c06ef4c20be9e6c6148a4b2e0 |
| 출처 메모 | uspto-grants-2013_05 |