Propionyl chloride → N-(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)propionamide

HRID 2098659노트

반응식

HRID 2098659 반응식
[Cl:1][C:2]1[N:3]=[C:4]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)[C:5]2[S:10][C:9]([NH2:11])=[CH:8][C:6]=2[N:7]=1.[C:18](Cl)(=[O:21])[CH2:19][CH3:20]>>[Cl:1][C:2]1[N:3]=[C:4]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)[C:5]2[S:10][C:9]([NH:11][C:18](=[O:21])[CH2:19][CH3:20])=[CH:8][C:6]=2[N:7]=1

참가 물질

3

반응물 2

HCID 62324Propionyl chlorideHCID 595928682-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-amine

생성물 1

HCID 86618387N-(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)propionamide

실험 절차

2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-amine (35 mg) was reacted with 23 μL of propionyl chloride via General Procedure G to give N-(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)propionamide.

출처 및 근거

ORD 기록
ord-8e40f9627343444cb46a653cbab698ff
출처 데이터셋
uspto-grants-2013_05
특허 번호
US08450315B2

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