4-Chlorophenol → HCID 57799623, 화합물

HRID 2100832노트

반응식

HRID 2100832 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.Cl[C:10]1[C:19]2[C:14](=[C:15]([CH3:20])[CH:16]=[CH:17][CH:18]=2)[CH:13]=[C:12]([NH:21][C:22]2[CH:26]=[C:25]([CH3:27])[NH:24][N:23]=2)[N:11]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:10]2[C:19]3[C:14](=[C:15]([CH3:20])[CH:16]=[CH:17][CH:18]=3)[CH:13]=[C:12]([NH:21][C:22]3[CH:26]=[C:25]([CH3:27])[NH:24][N:23]=3)[N:11]=2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 46844-ChlorophenolHCID 57799612HCID 57799612, 화합물

생성물 1

HCID 57799623HCID 57799623, 화합물

실험 절차

Similar procedure as described in example 10 was used, starting from 4-chloro-phenol and (1-chloro-5-methyl-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give [1-(4-chloro-phenoxy)-5-methyl-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 366(MH+).

출처 및 근거

ORD 기록
ord-d03ee36bafa544cf82eb35ebc5490129
출처 데이터셋
uspto-grants-2009_08
특허 번호
US07572809B2

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