Diethylene Glycol Monoethyl Ether → HCID 178468022, 화합물

반응식

Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[CH:16][NH:15][N:14]=2)[N:3]=1.[CH2:18]([O:20][CH2:21][CH2:22][O:23][CH2:24][CH2:25][OH:26])[CH3:19]>>[CH2:18]([O:20][CH2:21][CH2:22][O:23][CH2:24][CH2:25][O:26][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[CH:16][NH:15][N:14]=2)[N:3]=1)[CH3:19]

참가 물질

반응물 2

HCID 8146Diethylene Glycol Monoethyl Ether

HCID 178478391HCID 178478391, 화합물

생성물 1

HCID 178468022HCID 178468022, 화합물

실험 절차

Similar procedure as described in example 10 was used, starting from (1-chloro-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine and 2-(2-ethoxy-ethoxy)-ethanol to give {1-[2-(2-ethoxy-ethoxy)-ethoxy]-isoquinolin-3-yl}-(1H-pyrazol-3-yl)-amine. LC-MS m/e 343(MH+).

출처 및 근거

ORD 기록: ord-302ccded5c4f422787f14855c413597d
출처 데이터셋: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07572809B2

반응 노트

불러오는 중…