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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2100942생성일: 2026년 10월 27일

1-Methyl-1H-pyrazole-4-boronic acid → (5-methyl-1H-pyrazol-3-yl)-[1-(1H-pyrazol-4-yl)-6-methoxy-isoquinolin-3-yl]-amine

https://huagongshe.com/reaction/2100942

반응식

참여 물질

역할이름HCID투입량
반응물1-Methyl-1H-pyrazole-4-boronic acidHCID 11263501—
반응물(1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amineHCID 57799674—
생성물(5-methyl-1H-pyrazol-3-yl)-[1-(1H-pyrazol-4-yl)-6-methoxy-isoquinolin-3-yl]-amineHCID 57799593—

반응 단계

Similar procedure as described in example 131 was used, starting from (1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine and N-methyl-pyrazole-4-boronic acid to give (5-methyl-1H-pyrazol-3-yl)-[1-(1H-pyrazol-4-yl)-6-methoxy-isoquinolin-3-yl]-amine. LC-MS m/e 335(MH+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07572809B2
출처 데이터셋uspto-grants-2009_08
ORD IDord-4210d8903b204f76b7feeb112fca378b
출처 메모uspto-grants-2009_08