3-cyclopropyl-1H-pyrazol-5-amine → HCID 57799822, 화합물

반응식

[C:1]([CH2:3][C:4]1[CH:12]=[C:11]([O:13][CH3:14])[C:10]([O:15][CH3:16])=[CH:9][C:5]=1[C:6](O)=[O:7])#[N:2].[NH2:17][C:18]1[CH:22]=[C:21]([CH:23]2[CH2:25][CH2:24]2)[NH:20][N:19]=1>>[CH:23]1([C:21]2[NH:20][N:19]=[C:18]([NH:17][C:1]3[NH:2][C:6](=[O:7])[C:5]4[C:4]([CH:3]=3)=[CH:12][C:11]([O:13][CH3:14])=[C:10]([O:15][CH3:16])[CH:9]=4)[CH:22]=2)[CH2:25][CH2:24]1

참가 물질

반응물 2

HCID 27580143-cyclopropyl-1H-pyrazol-5-amine

HCID 126032022-(Cyanomethyl)-4,5-dimethoxybenzoic acid

생성물 1

HCID 57799822HCID 57799822, 화합물

실험 절차

Similar procedure as described in example 2c was used, starting from 2-cyanomethyl-4,5-dimethoxy-benzoic acid and 3-amino-5-cyclopropylpyrazol to give 3-(5-Cyclopropyl-1H-pyrazol-3-ylamino)-6,7-dimethoxy-2H-isoquinolin-1-one. LC-MS: m/e 327 (MH+).

출처 및 근거

ORD 기록: ord-6eadeb02bdea484399b17e456a46516e
출처 데이터셋: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07572809B2

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