1H-Pyrazol-3-amine, 5-methyl- → HCID 178486651, 화합물
반응식
[Br:1][C:2]1[C:3]([O:14][CH3:15])=[CH:4][C:5]([CH2:11][C:12]#[N:13])=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[NH2:16][C:17]1[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=1>C(O)(=O)C>[Br:1][C:2]1[CH:10]=[C:6]2[C:5]([CH:11]=[C:12]([NH:16][C:17]3[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=3)[N:13]=[C:7]2[OH:9])=[CH:4][C:3]=1[O:14][CH3:15]참가 물질
4
실험 절차
Similar procedure as described in example 9B was used, starting from 5-Bromo-2-cyanomethyl-4-methoxy-benzoic acid, 3-amino-5-methylpyrazol and acetic acid to give 7-Bromo-6-methoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinolin-1-ol. LC-MS: m/e 349 (MH+).
출처 및 근거
- ORD 기록
- ord-b664972ad2d842b09d707147cee698a0
- 출처 데이터셋
- uspto-grants-2009_08
- 특허 번호
- US07572809B2
반응 노트
불러오는 중…