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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2101184생성일: 2026년 10월 27일

N-Piperidinoethanol → [1-Isopropoxy-6-methoxy-7-(2-piperidin-1-yl-ethoxy)-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine

https://huagongshe.com/reaction/2101184

반응식

참여 물질

역할이름HCID투입량
반응물N-PiperidinoethanolHCID 18232—
반응물(7-Fluoro-1-isopropoxy-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amineHCID 57799513—
생성물[1-Isopropoxy-6-methoxy-7-(2-piperidin-1-yl-ethoxy)-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amineHCID 57799599—

반응 단계

Similar procedure as described in example 378 was used, starting from 2-Piperidin-1-yl-ethanol and (7-Fluoro-1-isopropoxy-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give [1-Isopropoxy-6-methoxy-7-(2-piperidin-1-yl-ethoxy)-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS: m/e 440(MH+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07572809B2
출처 데이터셋uspto-grants-2009_08
ORD IDord-121b4e70f7cf461fafd81d007f61d188
출처 메모uspto-grants-2009_08