참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 3-Bromo-2-chloro-4-(4-chlorophenyl)pyridine | HCID 57799367 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-Bromo-4-(4-chlorophenyl)-2-hydrazinylpyridine | HCID 57799454 | — |
반응 단계
A mixture of 3-bromo-2-chloro-4-(4-chlorophenyl)pyridine (10 g, 33 mmol), pyridine (50 mL) and hydrazine monohydrate (4.8 g, 96 mmol) was heated to 120° C. for 16 h. After cooling to room temperature, water (300 mL) was added, which caused solid desired product to precipitate. This was filtered, washed with water (2×50 mL), and dried to obtain the title compound as a pale yellow solid (6 g), which was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07572808B2 |
|---|
| 출처 데이터셋 | uspto-grants-2009_08 |
|---|
| ORD ID | ord-b19a41e389964ee2b2d4ca5d7f604812 |
|---|
| 출처 메모 | uspto-grants-2009_08 |
|---|
