Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 1-(4-Chlorophenyl)-2-(2,4-dichlorophenyl)ethane-1,2-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 2-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)ethan-1-one | HCID 21984867 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 1-(4-Chlorophenyl)-2-(2,4-dichlorophenyl)ethane-1,2-dione | HCID 22066077 | — |
반응 단계
To a solution of 100 g (0.33 mol) of 2-(4-chlorophenyl)-1-(2,4-dichlorophenyl)ethanone in 1 L of DMSO, 75 g (0.42 mol) of NBS was added and the mixture was stirred over a weekend. The reaction was poured into 8 L of water and stirred for 30 min. The yellow solid formed was filtered and dried. This solid was purified by passing through a plug of 1 Kg of silica gel using hexane and 5% EtOAc-hexane to isolate the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07572785B2 |
| 출처 데이터셋 | uspto-grants-2009_08 |
| ORD ID | ord-11ba3276fe4b41df9cb6413a9ad8212a |
| 출처 메모 | uspto-grants-2009_08 |