Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromomethylcyclopropane → 1-(Cyclopropylmethyl)-2-(2-methylpropyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromomethylcyclopropane | HCID 81503 | — |
| 반응물 | 2-(2-methylpropyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 67405196 | — |
| 생성물 | 1-(Cyclopropylmethyl)-2-(2-methylpropyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 67405485 | — |
반응 단계
Synthesized as described in Example 4 using 2-(2-methylpropyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile and (bromomethyl)cyclopropane. 1H NMR (400 MHz, CDCl3) δ 7.50 (d, J=9.2 Hz, 1H), 7.48 (d, J=9.2 Hz, 1H), 6.56 (d, J=1.7 Hz, 1H), 4.05 (d, J=6.6 Hz, 2H), 2.67 (t, J=7.1 Hz, 2H), 2.07 (m, 1H), 1.15 (m, 1H), 1.03 (d, J=6.6 Hz, 6H), 0.58 (m, 2H), 0.35 (m, 2H); MS (ES) m/z 321 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07572820B2 |
| 출처 데이터셋 | uspto-grants-2009_08 |
| ORD ID | ord-9d16a2fae09c49309455acb80ea8093b |
| 출처 메모 | uspto-grants-2009_08 |