Sulfuryl chloride → 4-Chloro-5-[(phenylmethyl)oxy]-1-(phenylsulfonyl)-2-propyl-1H-indole

HRID 2102027노트

반응식

HRID 2102027 반응식
[C:1]1([CH2:7][O:8][C:9]2[CH:10]=[C:11]3[C:15](=[CH:16][CH:17]=2)[N:14]([S:18]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)(=[O:20])=[O:19])[C:13]([CH2:27][CH2:28][CH3:29])=[CH:12]3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:33])(=O)=O>>[Cl:33][C:10]1[C:9]([O:8][CH2:7][C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[CH:17][CH:16]=[C:15]2[C:11]=1[CH:12]=[C:13]([CH2:27][CH2:28][CH3:29])[N:14]2[S:18]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:20])=[O:19]

참가 물질

3

반응물 2

HCID 24648Sulfuryl chlorideHCID 578001035-[(Phenylmethyl)oxy]-1-(phenylsulfonyl)-2-propyl-1H-indole

생성물 1

HCID 578004814-Chloro-5-[(phenylmethyl)oxy]-1-(phenylsulfonyl)-2-propyl-1H-indole

실험 절차

Synthesized as described in Example 22C from 5-[(phenylmethyl)oxy]-1-(phenylsulfonyl)-2-propyl-1H-indole and sulfuryl chloride: MS (ES) m/z 441 (M+1).

후처리

  1. customSynthesized

출처 및 근거

ORD 기록
ord-90fc2cbcf73f44a28496cd482c2fdec8
출처 데이터셋
uspto-grants-2009_08
특허 번호
US07572820B2

반응 노트

불러오는 중…