Bromine → HCID 57803105, 화합물

HRID 2102487노트

반응식

HRID 2102487 반응식
[Cl:1][C:2]1[C:3]2[N:4]([CH:8]=[C:9]([C:11]3[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[CH:12]=3)[N:10]=2)[CH:5]=[CH:6][N:7]=1.[Br:19]Br>C(O)(=O)C>[Br:19][C:8]1[N:4]2[CH:5]=[CH:6][N:7]=[C:2]([Cl:1])[C:3]2=[N:10][C:9]=1[C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[CH:12]=1

참가 물질

4

반응물 2

HCID 24408BromineHCID 578031348-Chloro-2-(3-methoxyphenyl)imidazo[1,2-a]pyrazine

생성물 1

HCID 57803105HCID 57803105, 화합물

시약·촉매·용매 1

HCID 176Acetic Acid용매2회

실험 절차

To the product from example 170 in acetic acid (10 mL) was added a solution of bromine in acetic acid (0.25 mmol, 1 mL). Concentration of the reaction mixture afforded crude 3-bromo-8-chloro-2-(3-methoxy-phenyl)-imidazo[1,2-a]pyrazine. MH+ (LCMS) 338.0(m/z).

출처 및 근거

ORD 기록
ord-8a85253990a34709980ac78506dab0db
출처 데이터셋
uspto-grants-2009_08
특허 번호
US07576085B2

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