Sodium Carbonate → 2-amino-1H-1,3-benzodiazole-5-carboxylic acid

HRID 2102852노트

반응식

HRID 2102852 반응식
[N:1]#[C:2]Br.[NH2:4][C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][C:13]=1[NH2:14])[C:8]([O-:10])=[O:9].C([O-])([O-])=O.[Na+].[Na+]>O>[NH2:1][C:2]1[NH:4][C:5]2[CH:6]=[C:7]([C:8]([OH:10])=[O:9])[CH:11]=[CH:12][C:13]=2[N:14]=1

참가 물질

5

반응물 3

HCID 10340Sodium CarbonateHCID 10476Cyanogen BromideHCID 69287573,4-Diaminobenzoate

생성물 1

HCID 133640612-amino-1H-1,3-benzodiazole-5-carboxylic acid

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A solution of cyanogen bromide (5M, 1.44 mL, 7.22 mmol) was slowly added to a suspension of 3,4-diaminobenzoate (1.0 g, 6.02 mmol) in water (10 mL). The mixture was stirred at room temperature for 24 hours. An aqueous solution of Na2CO3 (10%) was added slowly until the product had precipitated as a brown solid (890 mg).

후처리

  1. customhad precipitated as a brown solid (890 mg)

출처 및 근거

ORD 기록
ord-c44ba3b4a8f440c296bd01650e439499
출처 데이터셋
uspto-grants-2009_08
특허 번호
US07576079B2

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