4-Piperidinamine → 4,8-bis-(2-chloro-phenyl)-2-(piperidin-4-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one

HRID 210322

반응식

HRID 210322 반응식
[Cl:1][c:2]1[c:3](-[c:8]2[c:9]3[c:10]([n:11][c:12]([S:14]([CH3:15])(=[O:16])=[O:17])[n:13]2)[n:18](-[c:23]2[c:24]([Cl:29])[cH:25][cH:26][cH:27][cH:28]2)[c:19](=[O:22])[cH:20][cH:21]3)[cH:4][cH:5][cH:6][cH:7]1.[NH:30]1[CH2:31][CH2:32][CH:33]([NH2:36])[CH2:34][CH2:35]1>>[Cl:1][c:2]1[c:3](-[c:8]2[c:9]3[c:10]([n:11][c:12]([NH:36][CH:33]4[CH2:32][CH2:31][NH:30][CH2:35][CH2:34]4)[n:13]2)[n:18](-[c:23]2[c:24]([Cl:29])[cH:25][cH:26][cH:27][cH:28]2)[c:19](=[O:22])[cH:20][cH:21]3)[cH:4][cH:5][cH:6][cH:7]1

참가 물질

3

반응물 2

HCID 4243614-PiperidinamineHCID 102255784,8-bis-(2-chloro-phenyl)-2-methanesulfonyl-8H-pyrido[2,3-d]pyrimidin-7-one

생성물 1

HCID 596395514,8-bis-(2-chloro-phenyl)-2-(piperidin-4-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one

출처 및 근거

ORD 기록
ord-ff2cfcc46dc745c1a58de1f299070152
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

연결된 노트

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