1,1,1-Trifluoro-2,4-pentanedione → HCID 11509542, 화합물

HRID 2104150노트

반응식

HRID 2104150 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]([F:12])([F:11])[F:10])=[CH:4][C:3]=1[C:13]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=O.[F:21][C:22]([F:30])([F:29])[C:23](=[O:28])[CH2:24][C:25](=O)[CH3:26]>CCCCCCC.C(OCC)(=O)C>[F:21][C:22]([F:30])([F:29])[C:23]([C:24]1[C:25]([CH3:26])=[N:1][C:2]2[C:3]([C:13]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[CH:4][C:5]([O:8][C:9]([F:12])([F:11])[F:10])=[CH:6][CH:7]=2)=[O:28]

참가 물질

4

반응물 2

HCID 739431,1,1-Trifluoro-2,4-pentanedioneHCID 767339(2-Amino-5-trifluoromethoxy-phenyl)-phenyl-methanone

생성물 1

HCID 11509542HCID 11509542, 화합물수율 63%

시약·촉매·용매 1

HCID 21899848Ethylacetate heptane용매

실험 절차

The title compound was prepared from (2-Amino-5-trifluoromethoxy-phenyl)-phenyl-methanone [example A6] and 1,1,1-trifluoro-2,4-pentanedione according to the procedure of example 1, except that the reaction time was of 44 h and heptane/ethyl acetate (10:1) was used. Yield: 63%; MS: m/z=399 (M).

출처 및 근거

ORD 기록
ord-665bd1ffe1b9419e9c54b11e6dd3a925
출처 데이터셋
uspto-grants-2009_08
특허 번호
US07576217B2

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