Chlorophenyl isocyanate → Ethyl 4-[3-({[(2-Chlorophenyl)Amino]Carbonyl}Amino)Phenyl]-8-(Trifluoromethyl)Quinoline-3-Carboxylate
반응식
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([O:24][CH2:25][CH3:26])=[O:23])[CH:5]=[CH:6][CH:7]=1.[Cl:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=1[N:34]=[C:35]=[O:36]>>[Cl:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=1[NH:34][C:35]([NH:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:19])[F:20])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([O:24][CH2:25][CH3:26])=[O:23])[CH:5]=[CH:6][CH:7]=1)=[O:36]참가 물질
3
실험 절차
The title compound was prepared from ethyl 4-(3-aminophenyl)-8-(trifluoromethyl)quinoline-3-carboxylate and 2-chlorophenyl isocyanate according to the procedure of Example 65. MS (ES) m/z 511.9.
출처 및 근거
- ORD 기록
- ord-5e620073a80d49729b425f47eabfa38d
- 출처 데이터셋
- uspto-grants-2009_08