[4-Chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone → {4-[({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Thio)Methyl]Phenyl}Acetic Acid
반응식
[C:1]([CH2:4][C:5]1[CH:21]=[CH:20][C:8]([CH2:9][S:10][C:11]2[CH:12]=[C:13](B(O)O)[CH:14]=[CH:15][CH:16]=2)=[CH:7][CH:6]=1)([OH:3])=[O:2].Cl[C:23]1[C:32]2[C:27](=[C:28]([C:33]([F:36])([F:35])[F:34])[CH:29]=[CH:30][CH:31]=2)[N:26]=[CH:25][C:24]=1[C:37]([C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1)=O>>[CH2:37]([C:24]1[CH:25]=[N:26][C:27]2[C:32]([C:23]=1[C:13]1[CH:12]=[C:11]([S:10][CH2:9][C:8]3[CH:20]=[CH:21][C:5]([CH2:4][C:1]([OH:3])=[O:2])=[CH:6][CH:7]=3)[CH:16]=[CH:15][CH:14]=1)=[CH:31][CH:30]=[CH:29][C:28]=2[C:33]([F:36])([F:34])[F:35])[C:39]1[CH:40]=[CH:41][CH:42]=[CH:43][CH:44]=1참가 물질
3
실험 절차
The title compound was prepared from 3-(4-carboxymethyl-benzylsulfanyl)phenylboronic acid and [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone according to the procedure of Example 1. MS (ES) m/z 541.9.
출처 및 근거
- ORD 기록
- ord-c9336be9bd2c41ca96c23df49104e1c8
- 출처 데이터셋
- uspto-grants-2009_08