4-Aminobenzonitrile → HCID 178466720, 화합물

HRID 2104947노트

반응식

HRID 2104947 반응식
C(OC1C=C(C=CC=1OC(C)C)/C=[N:8]/[C:9]1[CH:16]=[CH:15][C:12]([C:13]#[N:14])=[CH:11][CH:10]=1)C.[CH2:24]([O:26][C:27]1[CH:28]=[C:29]([O:36][CH:37]([CH3:39])[CH3:38])[C:30]([F:35])=[C:31]([CH:34]=1)[CH:32]=O)[CH3:25].NC1C=CC(C#N)=CC=1>>[CH2:24]([O:26][C:27]1[CH:28]=[C:29]([O:36][CH:37]([CH3:39])[CH3:38])[C:30]([F:35])=[C:31]([CH:34]=1)/[CH:32]=[N:8]/[C:9]1[CH:16]=[CH:15][C:12]([C:13]#[N:14])=[CH:11][CH:10]=1)[CH3:25]

참가 물질

4

반응물 3

HCID 133964-AminobenzonitrileHCID 862472095-Ethoxy-2-fluoro-3-isopropoxybenzaldehydeHCID 178466719HCID 178466719, 화합물

생성물 1

HCID 178466720HCID 178466720, 화합물

실험 절차

According to the procedure for Intermediate 1.1, Intermediate 7.2 (3.13 g, 13.8 mmol) and 4-aminobenzonitrile (1.63 g, 13.8 mmol) afforded 4.45 g of Intermediate 7.3 as a yellow solid.

출처 및 근거

ORD 기록
ord-f44da0a1c013445b93bc180ffc769a6f
출처 데이터셋
uspto-grants-2009_08
특허 번호
US07576098B2

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