1-Methyl-3-phenyl-1H-1,2,4-triazole → HCID 57803888, 화합물

HRID 2105071노트

반응식

HRID 2105071 반응식
C(C1C=C(C(C2N(C)N=C(C3C=CC=CC=3)N=2)O)C=CC=1)C.[CH3:23][N:24]1[CH:28]=[N:27][C:26]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[N:25]1.[F:35][C:36]1[CH:43]=[C:42]([F:44])[C:41]([O:45][CH3:46])=[CH:40][C:37]=1[CH:38]=[O:39]>>[F:35][C:36]1[CH:43]=[C:42]([F:44])[C:41]([O:45][CH3:46])=[CH:40][C:37]=1[CH:38]([C:28]1[N:24]([CH3:23])[N:25]=[C:26]([C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)[N:27]=1)[OH:39]

참가 물질

4

반응물 3

HCID 108774081-Methyl-3-phenyl-1H-1,2,4-triazoleHCID 57803786(3-ethylphenyl)(2-methyl-5-phenyl-2H-1,2,4-triazol-3-yl)methanolHCID 578038672,4-Difluoro-5-methoxybenzaldehyde

생성물 1

HCID 57803888HCID 57803888, 화합물수율 74.1%

실험 절차

According to the procedure for Intermediate 370.2, 1-methyl-3-phenyl-1H-1,2,4-triazole (70 mg, 0.44 mmol) and Intermediate 391.1 (80 mg, 0.48 mmol) afforded 108 mg of Intermediate 391.2 as a white solid. LCMS 332.28 (M+H).

출처 및 근거

ORD 기록
ord-93d4bd16c2cf426cb505b58f83242f38
출처 데이터셋
uspto-grants-2009_08
특허 번호
US07576098B2

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