Ethyl 5-nitro-1H-indole-2-carboxylate → HCID 10286804, 화합물

HRID 2105582노트

반응식

HRID 2105582 반응식
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([C:11]([O:13]CC)=O)=[CH:5]2.[N+]([C:19]1[CH:20]=[C:21]2[C:25](=[CH:26][CH:27]=1)N[C:23]([C:28]([O:30]CC)=O)=[CH:22]2)([O-])=O>>[C:4]([C:27]1[CH:19]=[CH:20][C:21](/[CH:22]=[CH:23]/[C:28]([NH:1][C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[NH:7][C:6]([CH2:11][OH:13])=[CH:5]3)=[O:30])=[CH:25][CH:26]=1)([CH3:8])([CH3:5])[CH3:3]

참가 물질

3

반응물 2

HCID 280312Ethyl 5-nitro-1H-indole-2-carboxylateHCID 10726872Ethyl 5-amino-1H-indole-2-carboxylate

생성물 1

HCID 10286804HCID 10286804, 화합물

실험 절차

Ethyl 5-aminoindole-2-carboxylate. Analogous to the procedure used to prepare Example 3, step (a), ethyl 5-nitroindole-2-carboxylate (2.3 g, 9.9 mmol, Acros) provided the title product. MS (ESI, pos. ion) m/z: 205 (M+1).

출처 및 근거

ORD 기록
ord-b995edc4c3b94f3caa8bcddb92ae5a55
출처 데이터셋
uspto-grants-2009_08
특허 번호
US07579347B2

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