Potassium Hydroxide → 3-(1-carboxyethoxy)-5-methyl-1-phenyl-1,2,4-1H-triazole
반응식
C([O:3][C:4]([CH:6]([O:8][C:9]1[N:13]=[C:12]([CH3:14])[N:11]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:10]=1)[CH3:7])=[O:5])C.[OH-].[K+]>C(O)C>[C:4]([CH:6]([O:8][C:9]1[N:13]=[C:12]([CH3:14])[N:11]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:10]=1)[CH3:7])([OH:5])=[O:3]참가 물질
4
실험 절차
Ten g of the compound of Example 7 was refluxed for 4 hours with 4.1 g of potassium hydroxide in 150 ml of ethanol and the product was collected by extraction with ethyl acetate. The extract was washed with water, dried and evaporated under vacuum, and the residue was recrystallized from toluene to obtain 2.1 g of the desired product, m.p. 157°-159°.
후처리
- customthe product was collected by extraction with ethyl acetate
- washThe extract was washed with water
- customdried
- customevaporated under vacuum
- customthe residue was recrystallized from toluene
출처 및 근거
- ORD 기록
- ord-d4f75632c6ef44ec9f5ef44d75695263
- 출처 데이터셋
- uspto-grants-1990_06
- 특허 번호
- US04931083
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