5-Phenyl-4-pentyn-1-ol → 4-Pentynal, 5-phenyl-

HRID 2106855노트

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HRID 2106855 반응식
[C:1]1([C:7]#[C:8][CH2:9][CH2:10][CH2:11][OH:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl.CCOCC>[C:1]1([C:7]#[C:8][CH2:9][CH2:10][CH:11]=[O:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

5

반응물 2

HCID 111374345-Phenyl-4-pentyn-1-olHCID 178418287HCID 178418287, 화합물

생성물 1

HCID 112406334-Pentynal, 5-phenyl-

시약·촉매·용매 2

HCID 3283Diethyl Ether용매HCID 6344Dichloromethane용매2회

실험 절차

A solution of 5-phenylpent-4-yn-1-ol (250 mg) in dry CH2Cl2 (2 ml) was added to a suspension of pyridinium chlorochromate (520 mg) in dry CH2Cl2 (3 ml). The mixture was stirred for 2.5 hours and diluted with ether, and the organic solution was decanted off. The oily residue was treated with ether (5×20 ml) and the extracts were washed successively with 5% NaHCO3, water and brine. After drying, the solvent was removed to yield 5-phenylpent-4-ynal.

후처리

  1. customthe organic solution was decanted off
  2. additionThe oily residue was treated with ether (5×20 ml)
  3. washthe extracts were washed successively with 5% NaHCO3, water and brine
  4. customAfter drying
  5. customthe solvent was removed

출처 및 근거

ORD 기록
ord-fabfe7c25191416990009946db6b4e9a
출처 데이터셋
uspto-grants-1990_06
특허 번호
US04931469

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