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2,3-Diphenylpropiononitrile → 2-Cyano-2-(2,4-dichlorophenyl)-1-(3-pyridyl) hexane

HRID 2107133
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HRID 2107133 반응식
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([CH2:12][CH2:13][CH2:14][CH3:15])[C:10]#[N:11].C1(C([CH2:25][CH2:26][CH2:27][CH3:28])C#N)C=CC=CC=1.C1(C(CC2C=CC=CC=2)[C:36]#[N:37])C=CC=CC=1.F[C:46]1C=C(C(CCC2C=CC=CC=2)C#N)C=CC=1.ClC1C=CC(C(CC(Cl)=C)C#N)=CC=1.ClC1C=CC=CC=1C(CCC1C=CC(Cl)=CC=1)C#N>>[C:10]([C:9]([C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1])([CH2:28][CH2:27][CH2:26][CH3:25])[CH2:12][C:13]1[CH:46]=[N:37][CH:36]=[CH:15][CH:14]=1)#[N:11]
참가 물질실험 절차출처 및 근거반응 노트

참가 물질

7

반응물 6

HCID 952962,3-DiphenylpropiononitrileHCID 977992-PhenylhexanenitrileHCID 123432572-(2,4-Dichlorophenyl)hexane nitrileHCID 230472792-(4-Chlorophenyl)4-chloro-4-pentene nitrileHCID 230473092-(2-Chlorophenyl)-4-(4chlorophenyl)butyro nitrileHCID 230473112-(3-Fluorophenyl)-4-phenylbutyro nitrile

생성물 1

HCID 150965092-Cyano-2-(2,4-dichlorophenyl)-1-(3-pyridyl) hexane

실험 절차

Examples 1, 4-5, 13, 14, 19-22, 24 and 25 were prepared in a similar manner and instead of 2-(2,4-dichlorophenyl)hexane nitrile using: 2-phenylhexane nitrile, 2,3-diphenylpropionitrile, 2-(3-fluorophenyl)-4-phenylbutyro nitrile, 2-(4-chlorophenyl)-2-hexen-5-yl nitrile, 2-(4-chlorophenyl)-7-octenyl nitrile, 2-(4-chlorophenyl)4-chloro-4-pentene nitrile and 2-(2-chlorophenyl)-4-(4chlorophenyl)butyro nitrile.

출처 및 근거

ORD 기록
ord-6a5c131a7b5c45bc942ef74f3e85217f
출처 데이터셋
uspto-grants-1990_06
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04933339

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