Ethyl 2-[(2-methylphenyl)amino]-4-thiazolecarboxylate → HCID 16769476, 화합물

HRID 2107263노트

반응식

HRID 2107263 반응식
[C:1]1([CH3:18])[C:2]([NH:7][C:8]2[S:9][CH:10]=[C:11]([C:13](OCC)=[O:14])[N:12]=2)=[CH:3][CH:4]=[CH:5][CH:6]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[C:1]1([CH3:18])[C:2]([NH:7][C:8]2[S:9][CH:10]=[C:11]([CH2:13][OH:14])[N:12]=2)=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 2

HCID 1284666Ethyl 2-[(2-methylphenyl)amino]-4-thiazolecarboxylateHCID 21226445Aluminium lithium hydride

생성물 1

HCID 16769476HCID 16769476, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

Following a procedure similar to that described in Preparation 15, the desired compound was prepared from 10 g of ethyl 2-o-toluidinothiazole-4-carboxylate, 2.9 g of lithium aluminum hydride and 200 ml of tetrahydrofuran. The resulting product was a brown oil having the following physical properties.

후처리

  1. customthat described in Preparation 15

출처 및 근거

ORD 기록
ord-c9f0ede297a740998ad68a5a2cd9e231
출처 데이터셋
uspto-grants-1990_06
특허 번호
US04933355

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