Ethyl bromopyruvate → Ethyl 2-isopropylaminothiazole-4-carboxylate

HRID 2107302노트

반응식

HRID 2107302 반응식
[CH:1]([NH:4][C:5]([NH2:7])=[S:6])([CH3:3])[CH3:2].Br[CH2:9][C:10](=O)[C:11]([O:13][CH2:14][CH3:15])=[O:12]>C(O)C>[CH:1]([NH:4][C:5]1[S:6][CH:9]=[C:10]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[N:7]=1)([CH3:3])[CH3:2]

참가 물질

4

반응물 2

HCID 66144Ethyl bromopyruvateHCID 1711921Urea, 1-isopropyl-2-thio-

생성물 1

HCID 15053549Ethyl 2-isopropylaminothiazole-4-carboxylate

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The reaction described in Preparation 42 was repeated, but using 3.7 g of isopropylthiourea, 7.4 g of ethyl bromopyruvate and 50 ml of ethanol, giving the title compound as a pale yellow oil.

후처리

  1. customThe reaction described in Preparation 42

출처 및 근거

ORD 기록
ord-975a0b793e334788b6c424fd96bd50b6
출처 데이터셋
uspto-grants-1990_06
특허 번호
US04933355

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