Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 2-[2-(N-isobutyl-N-methylamino)benzylthio]imidazo[4,5-b]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2-(N-isobutyl-N-methylamino)benzyl chloride hydrochloride | HCID 14839444 | — |
| 반응물 | HCID 178527819 | HCID 178527819 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-[2-(N-isobutyl-N-methylamino)benzylthio]imidazo[4,5-b]pyridine | HCID 14839445 | — |
반응 단계
2-Mercaptoimidazo[4,5-b]pyridine and 2-(N-isobutyl-N-methylamino)benzyl chloride hydrochloride were reacted in an aqueous ethanol solution in the presence of sodium hydroxide to obtain 2-[2-(N-isobutyl-N-methylamino)benzylthio]imidazo[4,5-b]pyridine in the same manner as in Example 1-(2). The obtained 2-[2-(N-isobutyl-N-methylamino)benzylthio]imidazo[4,5-b]pyridine was oxidized by m-chloroperbenzoic acid in chloroform in the same manner as in Example 9-(3) to give 2-[2-(N-isobutyl-N-methylamino)benzylsulfinyl]imidazo[4,5-b]pyridine as a pale yellow crystalline product. m.p.: 116°-118° C. (decompn.)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04933458 |
| 출처 데이터셋 | uspto-grants-1990_06 |
| ORD ID | ord-97719df404c04c68acd7b9b27659e1bf |
| 출처 메모 | uspto-grants-1990_06 |