3-Bromo-4-methylpyridine → 3-Ethynyl-4-methylpyridine

HRID 2109184노트

반응식

HRID 2109184 반응식
Br[C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH3:8].N[C:10]1N=CC(C2N=NN(C3C=C(C=CC=3C)C(NC3C=C(C(C)(C)C)C=C(NS(C)(=O)=O)C=3OC)=O)C=2)=C[CH:11]=1>>[C:10]([C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH3:8])#[CH:11]

참가 물질

3

반응물 2

HCID 8176303-Bromo-4-methylpyridineHCID 210970953-[4-(6-amino-pyridin-3-yl)-[1,2,3]triazol-1-yl]-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamide

생성물 1

HCID 219548323-Ethynyl-4-methylpyridine

실험 절차

3-Ethynyl-4-methyl-pyridine was prepared from 3-bromo-4-methyl-pyridine in the same manner as 2-amino-3-ethynyl pyridine (Example 15).

출처 및 근거

ORD 기록
ord-efe6581502f84c8389813ae641a57e1a
출처 데이터셋
uspto-grants-2009_04
특허 번호
US07514458B2

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