Furan, 2-bromo- → (R)-3'-(Furan-2-yl)spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-one

HRID 2109426

반응식

HRID 2109426 반응식
[O:1]1[C@@:5]2([CH:10]3[CH2:11][CH2:12][N:7]([CH2:8][CH2:9]3)[CH2:6]2)[CH2:4][NH:3][C:2]1=[O:13].Br[C:15]1[O:16][CH:17]=[CH:18][CH:19]=1>>[O:16]1[CH:17]=[CH:18][CH:19]=[C:15]1[N:3]1[CH2:4][C@:5]2([CH:10]3[CH2:11][CH2:12][N:7]([CH2:8][CH2:9]3)[CH2:6]2)[O:1][C:2]1=[O:13]

참가 물질

3

반응물 2

HCID 2776190Furan, 2-bromo-HCID 5310971AR-R-17779

생성물 1

HCID 57634249(R)-3'-(Furan-2-yl)spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-one

실험 절차

The title compound was prepared by a method analogous to that described in Preparation 3 from (S)-spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one and 2-bromofuran. The title compound (1.49 g) was obtained as a pale-yellow solid, m/z 249 (MH+).

후처리

  1. customThe title compound was prepared by a method analogous to

출처 및 근거

ORD 기록
ord-7f11c7d4e41148e68e19f49c7ad9f87f
출처 데이터셋
uspto-grants-2009_04
특허 번호
US07514567B2

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