3-Bromofuran → (R)-3'-(Furan-3-yl)spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-one

HRID 2109460노트

반응식

HRID 2109460 반응식
[O:1]1[C@@:5]2([CH:10]3[CH2:11][CH2:12][N:7]([CH2:8][CH2:9]3)[CH2:6]2)[CH2:4][NH:3][C:2]1=[O:13].Br[C:15]1[CH:19]=[CH:18][O:17][CH:16]=1>>[O:17]1[CH:18]=[CH:19][C:15]([N:3]2[CH2:4][C@:5]3([CH:10]4[CH2:11][CH2:12][N:7]([CH2:8][CH2:9]4)[CH2:6]3)[O:1][C:2]2=[O:13])=[CH:16]1

참가 물질

3

반응물 2

HCID 891643-BromofuranHCID 5310971AR-R-17779

생성물 1

HCID 57634259(R)-3'-(Furan-3-yl)spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-one

실험 절차

The title compound was prepared by a method analogous to that described in Preparation 3 from (S)-spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one and 3-bromofuran. The title compound (445 mg) was obtained as a pale-yellow solid, m/z 249 (MH+).

후처리

  1. customThe title compound was prepared by a method analogous to

출처 및 근거

ORD 기록
ord-b4ce93d1aeee46f3b4f57c5f1a8eaa4e
출처 데이터셋
uspto-grants-2009_04
특허 번호
US07514567B2

반응 노트

불러오는 중…