AR-R-17779 → HCID 11738867, 화합물

HRID 2109466노트

반응식

HRID 2109466 반응식
[O:1]1[C@@:5]2([CH:10]3[CH2:11][CH2:12][N:7]([CH2:8][CH2:9]3)[CH2:6]2)[CH2:4][NH:3][C:2]1=[O:13].Br[C:15]1[CH:19]=[C:18]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=2)[O:17][CH:16]=1>[Cu]I>[N:21]1[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=1[C:18]1[O:17][CH:16]=[C:15]([N:3]2[CH2:4][C@:5]3([CH:10]4[CH2:11][CH2:12][N:7]([CH2:8][CH2:9]4)[CH2:6]3)[O:1][C:2]2=[O:13])[CH:19]=1

참가 물질

4

반응물 2

HCID 5310971AR-R-17779HCID 576342462-(4-Bromofuran-2-yl)pyridine

생성물 1

HCID 11738867HCID 11738867, 화합물

시약·촉매·용매 1

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)촉매

실험 절차

The title compound was prepared by a method analogous to that described in Preparation 3 from (S)-spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one and 3-bromo-5-(2-pyridyl)-furan with 2 equivalents of copper (I) iodide. The title compound (90 mg) was obtained as a pale yellow solid, m/z 342 (MH+).

후처리

  1. customThe title compound was prepared by a method analogous to

출처 및 근거

ORD 기록
ord-5879e6bad96441b0a020d584de063a02
출처 데이터셋
uspto-grants-2009_04
특허 번호
US07514567B2

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