HCID 15512340, 화합물 → HCID 9959163, 화합물
반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][NH:9][C:10]([C:12]1[C:13]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[CH2:24][NH2:25])=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:11].N1C=CC=CC=1CCNC(C1C(C2C=CC=CC=2C([C:51]([O:53][CH:54]([CH3:65])[C:55]2[CH:60]=[CH:59][C:58]([C:61]([F:64])([F:63])[F:62])=[CH:57][CH:56]=2)=[O:52])N)=CC=CC=1)=O>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][NH:9][C:10]([C:12]1[C:13]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[CH2:24][NH:25][C:51]([O:53][CH:54]([CH3:65])[C:55]2[CH:56]=[CH:57][C:58]([C:61]([F:62])([F:64])[F:63])=[CH:59][CH:60]=2)=[O:52])=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:11]참가 물질
3
실험 절차
From 0.3 mmol of 2′-aminomethylbiphenyl-2-carboxylic acid 2-(2-pyridyl)-ethylamide (precursor 5d) and α-methyl-4-trifluoromethyl)benzyl N-succinimidocarbonate (precursor 4c), according to the general working procedure 170 mg of 2′-(α-methyl-4-(trifluoromethyl)benzyloxycarbonyl-aminomethyl)biphenyl-2-carboxylic acid 2-(2-pyridyl)ethylamide were obtained as a racemate. MS (ES+): m/e=548 (M+1).
후처리
- customwere obtained as a racemate
출처 및 근거
- ORD 기록
- ord-fbd3ee7888f64e6ab369ea46aff154e2
- 출처 데이터셋
- uspto-grants-2009_04