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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2112447생성일: 2026년 10월 26일

2,4-Difluorobenzenesulfonyl Chloride → 1-[(2,4-Difluorophenyl)sulfonyl]-4-(1-piperazinyl)-1H-indole Hydrochloride

https://huagongshe.com/reaction/2112447

반응식

참여 물질

역할이름HCID투입량
반응물2,4-Difluorobenzenesulfonyl ChlorideHCID 2734273—
반응물tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylateHCID 22015386—
생성물1-[(2,4-Difluorophenyl)sulfonyl]-4-(1-piperazinyl)-1H-indole HydrochlorideHCID 10201828—

반응 단계

The title compound was prepared from 4-(4-boc-piperazinyl)-indole and 2,4-di-fluorophenylsulfonylchloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.41 (br, 1H), 8.24 (m, 1H), 7.75 (m, 1H), 7.58 (m, 1H), 7.47-7.33 (m, 2H), 7.23 (t, J=8 Hz, 1H), 6.99 (d, J=5 Hz, 1H), 6.70 (d, J=8 Hz, 1H), 3.25 (m, 8H). MS (ESI+) for m/z 378 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07524839B2
출처 데이터셋uspto-grants-2009_04
ORD IDord-adece8a33ad846c884f4b20cbb1a35a1
출처 메모uspto-grants-2009_04