Trifluoroacetic acid → HCID 68827546, 화합물
반응식
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[N:22]=[CH:21][N:20]=[C:19]3[C:15]=2[N:16]([CH2:24][C:25]#[C:26][CH3:27])[C:17](=[O:23])[NH:18]3)[CH2:10][CH2:9]1)=O)(C)(C)C.[F:28][C:29]([F:34])([F:33])[C:30]([OH:32])=[O:31]>>[F:28][C:29]([F:34])([F:33])[C:30]([OH:32])=[O:31].[CH2:24]([N:16]1[C:15]2[C:19](=[N:20][CH:21]=[N:22][C:14]=2[N:11]2[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)[NH:18][C:17]1=[O:23])[C:25]#[C:26][CH3:27]참가 물질
3
실험 절차
4-[7-(2-Butynyl)-8-oxo-8,9-dihydro-7H-purin-6-yl]piperazine-1-carboxylic acid t-butyl ester (compound 61e) (12 mg) was dissolved in trifluoroacetic acid. This reaction solution was stirred at room temperature for five minutes, and then concentrated. The residue was purified by reverse phase high performance liquid chromatography to give the title compound (8.86 mg).
후처리
- concentrationconcentrated
- customThe residue was purified by reverse phase high performance liquid chromatography
출처 및 근거
- ORD 기록
- ord-cce7e992ac5047089da1151eaf1583c8