tert-butyl N-{[(2S)-piperidin-2-yl]methyl}carbamate → ((S)-1-{1-[4-(4-Fluoro-phenyl)-1-methyl-1H-pyrazol-3-yl]-methanoyl}-piperidin-2-ylmethyl)-carbamic acid
반응식
C([O:5][C:6](=[O:15])[NH:7][CH2:8][C@@H:9]1[CH2:14][CH2:13][CH2:12][CH2:11][NH:10]1)(C)(C)C.[F:16][C:17]1[CH:22]=[CH:21][C:20]([C:23]2[C:24]([C:29](O)=[O:30])=[N:25][N:26]([CH3:28])[CH:27]=2)=[CH:19][CH:18]=1>>[F:16][C:17]1[CH:18]=[CH:19][C:20]([C:23]2[C:24]([C:29]([N:10]3[CH2:11][CH2:12][CH2:13][CH2:14][C@H:9]3[CH2:8][NH:7][C:6](=[O:15])[OH:5])=[O:30])=[N:25][N:26]([CH3:28])[CH:27]=2)=[CH:21][CH:22]=1참가 물질
3
실험 절차
The title compound (3.96 g) was prepared from (S)-1-piperidin-2-ylmethyl-carbamic acid tert butyl ester (2.14 g) and 4-(4-fluoro-phenyl)-1-methyl-1H-pyrazol-3-yl carboxylic acid (2.20 g) according to the method of D40.
출처 및 근거
- ORD 기록
- ord-8e193f5fdb654ad08510186e1c6e5107
- 출처 데이터셋