3-Isoxazolamine → 3-(6-ethanesulfonylpyridin-3-yloxy)-5-(2-hydroxy-1-methyl-ethoxy)-N-(isoxazol-3-yl)benzamide

반응식

CO[C:3](=[O:15])[C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[C:6](OCOC)[CH:5]=1.Br[C:17]1[CH:18]=[CH:19][C:20]([S:23]([CH2:26][CH3:27])(=[O:25])=[O:24])=[N:21][CH:22]=1.[O:28]([CH2:36][C@H:37]([OH:39])[CH3:38])[Si](C(C)(C)C)(C)C.[NH2:40][C:41]1[CH:45]=[CH:44][O:43][N:42]=1>>[CH2:26]([S:23]([C:20]1[N:21]=[CH:22][C:17]([O:10][C:8]2[CH:9]=[C:4]([CH:5]=[C:6]([O:39][CH:37]([CH3:38])[CH2:36][OH:28])[CH:7]=2)[C:3]([NH:40][C:41]2[CH:45]=[CH:44][O:43][N:42]=2)=[O:15])=[CH:18][CH:19]=1)(=[O:25])=[O:24])[CH3:27]