Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-4'-methoxyacetophenone → 2-(3-Chloro-thiophen-2-yl)-5-(4-methoxy-phenyl)-oxazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-4'-methoxyacetophenone | HCID 412889 | — |
| 반응물 | 3-Chlorothiophene-2-carbonyl chloride | HCID 2735824 | — |
| 생성물 | 2-(3-Chloro-thiophen-2-yl)-5-(4-methoxy-phenyl)-oxazole | HCID 22147907 | — |
반응 단계
3-Choloro-thiophene-2-carboxylic acid-[2-(4-methoxy-phenyl)-2-oxo-ethyl]-amide: The title compound was prepared from 3-chloro-thiophene-2-carbonyl chloride and 2-amino-4′-methoxy acetophenone by a procedure similar to Example 93a as an orange solid. 1H NMR (DMSO-d6): 8.30 (s, NH), 8.02 (d, J=9.0 Hz, 1H), 7.89 (d, J=6.6 Hz, 2H), 7.20 (d, J=6.0 Hz, 2H), 7.10 (d, J=8.7 Hz, 1H), 4.80 (d, J=5.4 Hz, 2H), 3.86 (s, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07435750B2 |
| 출처 데이터셋 | uspto-grants-2008_10 |
| ORD ID | ord-ebbe3cd86fdd4e9d9102fa312261485b |
| 출처 메모 | uspto-grants-2008_10 |