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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2114982생성일: 2026년 10월 26일

5-Amino-2-oxindole → 2-Oxo-N-(2-oxo-2,3-dihydro-1H-indol-5-yl)-2-(4-p-tolyloxy-piperidin-1-yl)-acetamide

https://huagongshe.com/reaction/2114982

반응식

참여 물질

역할이름HCID투입량
반응물5-Amino-2-oxindoleHCID 2773213—
반응물Oxo-(4-p-tolyloxy-piperidin-1-yl)-acetic acidHCID 69100252—
생성물2-Oxo-N-(2-oxo-2,3-dihydro-1H-indol-5-yl)-2-(4-p-tolyloxy-piperidin-1-yl)-acetamideHCID 69100718—

반응 단계

The title compound is prepared from oxo-(4-p-tolyloxy-piperidin-1-yl)-acetic acid and 5-amino-1,3-dihydro-indol-2-one according to the method described in Example 2. The filtered crystals are purified by column chromatography using Kieselgel 60 (Merck) as adsorbent and toluene:methanol=4:1 as eluent. Melting Point: 176-178° C. (diethyl ether)

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07435744B2
출처 데이터셋uspto-grants-2008_10
ORD IDord-52765ca6e0a44ddea76137d35145b8fb
출처 메모uspto-grants-2008_10