4-Benzylpiperidine → 2-(4-Benzyl-piperidin-1-yl)-N-(3-nitro-phenyl)-acetamide

HRID 2115100노트

반응식

HRID 2115100 반응식
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-:14])=[O:13])[CH:7]=1)=[O:4].[CH2:15]([CH:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>C(OCC)C>[CH2:15]([CH:22]1[CH2:27][CH2:26][N:25]([CH2:2][C:3]([NH:5][C:6]2[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-:14])=[O:13])[CH:7]=2)=[O:4])[CH2:24][CH2:23]1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

참가 물질

4

반응물 2

HCID 317384-BenzylpiperidineHCID 5320662-chloro-N-(3-nitrophenyl)acetamide

생성물 1

HCID 89045912-(4-Benzyl-piperidin-1-yl)-N-(3-nitro-phenyl)-acetamide

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

The title compound is prepared from 2-chloro-N-(3-nitro-phenyl)-acetamide [Tetrahedron Lett. 39, 7459. (1998)] and 4-benzyl-piperidine according to the method described in Example 142b. Melting Point: 102-104° C. (diethylether)

출처 및 근거

ORD 기록
ord-9efa444e52454bf488a4821bdaa0789e
출처 데이터셋
uspto-grants-2008_10
특허 번호
US07435744B2

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